Biophysics and Bioinformatics Workshop 2001

Graduate Programmes:

Dynamics and Evolution of Cellular and Macromolecular Processes (GK-DFG, Berlin, Germany)

Bioinformatics Graduate Programme (IGERT, Boston, USA)

Biophysics and Bioinformatics Workshop Berlin 2001

Organizers:     R. Heinrich and A. Herrmann (Berlin), C. DeLisi and T. Tullius (Boston)

Local Committee:     J. Farwer, R. Heinrich, A. Herrmann, H. Herzel, D. Holste, E. Klipp, E. Knapp, A. Rappert, and M. Sternberg

Venue:     Wissenschaftsforum Berlin, Am Gendarmenmarkt, Markgrafenstr. 37, 10117 Berlin, Germany

Time:     22. August - 25. August 2001

Schedule:

Tuesday, 21. August 2001

18:00

Reception
Wissenschaftsforum Berlin, Am Gendarmenmarkt

Wednesday, 22. August 2001

Morning session: Conformation and Association of Biomolecules

Chairman: Dirk Holste

9:00 - 9:10	Opening Reinhart Heinrich
9:10 - 9:30	Paul-Robert Königs Graduate Schools and Transatlantic Cooperation
9:30 - 10:00	Charles DeLisi Some brief remarks on Bioinformatics at Boston University and research in the Molecular Engineering Research Laboratory
10:00 - 10:30	Ernst Walter Knapp Modeling electron transfer in proteins: bacterial reaction centers and photolyase
10:30 - 11:00	Sandor Vajda Studying the origin of binding specificity by protein mapping
11:00 - 11:30	Coffee break
11:30 - 11:50	Andreas Modler Amyloid formation as a fractal growth process of fibres via oligomeric intermediates
11:50 - 12:20	Zhiping Weng Protein structure comparison and statistical significance: analysis of the structure database
12:20 - 12:40	Jochen Farwer A contact energy function optimized to recognize the native fold of a protein
12:40 - 14:30	Lunch time

Poster session

14:30 - 16:30

Presentations and abstracts

Afternoon session: Conformation and Association of Biomolecules

Chairman: Angelika Rappert

17:00 - 17:20	Dragan Popovic Electrostatics of native and artificial cytochrome b
17:20 - 17:50	Klaus-Peter Hofmann Activation G-protein coupled receptors: the rhodopsin model
17:50 - 18:10	Antje Pohl ABC proteins as lipid transporters
18:10 - 18:30	Astrid Tannert Fluorescence life time determination of fluorescent lipid analogs in different environments: A method for determation of the localization and organization of phospholipids in the bile

Thursday, 23. August 2001

Morning session: Cellular Signaling

Chairman: Antje Pohl

9:00 - 9:30	Reinhart Heinrich Modeling of signal transduction networks: Wnt/catenin pathway
9:30 - 9:50	Angelika Rappert Secondary lymphoid tissue chemokine (CCL21) activates CXCR3 to trigger a Cl- current and chemotaxis in murine microglia
9:50 - 10:20	Andreas Herz Discrimination of sensory stimuli based on the information contained in single spike trains
10:20 - 11:00	Coffee break
11:00 - 11:30	Thomas Höfer GATA-3 transcriptional memory in T helper lymphocytes: a mathematical model of steady-state and temporal behaviour
11:30 - 11:50	Christian Zemlin Modeling excitation propagation in the human heart

Morning session: Proteome Analysis

Chairman: Jochen Farwer

11:50 - 12.20	Hermann-Georg Holzhütter Proteasomes: How do they work?
12:20 - 14:00	Lunch time
Afternoon	Visit of the Reichstag and sight-seeing tour

Friday, 24. August 2001

Morning session: Proteome Analysis

Chairman: Jochen Farwer

9:00 - 9:30	Scott Mohr Bioinformatic Analysis of Mitochondrial Proteomes -
9:30 - 9:50	Robert Anderson Profile-profile alignment: new scoring metrics for detecting distant evolutionary relationships
9:50 - 10:10	Björn Peters Assessment of proteasomal cleavage rates from time-courses of product formation
10:10 - 11:00	Coffee break

Poster session

11:00 - 13:00	Presentations and abstracts
13:00 - 15:00	Lunch time

Afternoon session: Metabolic Modeling

Chairman: Andreas Modler

15:00 - 15:30	Edda Klipp Temporal change in gene expression pattern in yeast due to osmotic stimulation: mathematical modeling and prediction
15:30 - 16:00	Stefan Schuster Metabolic pathway analysis and game-theoretical description of the evolution of ATP producing pathways
16:00 - 16:20	Ionela Zevedei-Oancea Treatment of multifunctional enzymes in metabolic pathway analysis
16:20 - 17:00	Coffee break

Afternoon session: Genomes

Chairman: Andreas Modler

17:00 - 17:30	Lev Levitin Prokaryotic promoter recognition as a statistical decision problem
17:30 - 17:50	Dirk Holste Repeats and compositional heterogeneity in human chromosome 22
17:50 - 18:10	Wolfram Liebermeister Independent component analysis of gene expresison data
19:30	Conference dinner

Saturday, 25. August 2001

Morning session: Genomes

Chairman: Ionela Zevedei-Oancea

9:00 - 9:30	Tom Tullius Mapping the structure of genomic DNA using a chemical probe
9:30 - 9:50	Martin Frith Detecting clusters of cis-elements in higher eukaryotic DNA
9:50 - 10:10	Dmitriy Leyfer In-silico expression profiling using EST databases
10:10 - 11:00	Coffee break
11:00 - 11:30	Hanspeter Herzel On the dynamic origin of isochores
11:30 - 11:50	Adnan Derti Classification of tumors by weighted gene expression committees
11:50 - 12:10	Itai Yanai Structure, function, and evolution of fusion link networks
12:10 - 12:30	Concluding remarks
12:30 - 14:00	Lunch time