Research projects
Mathematical modeling of complex biological phenomena and diseases is an important approach to combine the accumulating amount of data in biological investigations and the increasing qualitative understanding of cellular operation in a productive way. The realization of genomic information in a biological instance is ensured by a complex network of processes. The dynamic behavior of such processes cant be understood intuitively. Only a comprehensive approach allows the understanding of complex system behavior like optimal regulation or adaptation. We use mathematical models to describe and investigate cellular processes and regulatory links from gene expression to metabolism.
For tools see our Tools section
PhD programs
IMPRS
International Max Planck Research School
for Computational Biology and Scientific Computing
more ...
for Computational Biology and Scientific Computing
LGS Molecular Biophysics
Leibniz Graduate School of Molecular Biophysics
more ...
Affiliated scientists: Matthias Reis,
Edda Klipp
SignGene
German-Israeli Research School "Frontiers in Cell Signaling and Gene Regulation"
more ...
Affiliated scientists: Edda Klipp
Junior research group
e:Bio Cellemental
The complexity of cellular networks is an outstanding challenge for documentation, visualisation and mathematical
modelling. In this project, we develop a new way to describe these networks that minimises the combinatorial complexity and allows an
automatic visualisation and export to mathematical models.
more ...
Cooperative research projects
SFB 618
Collaborative Research Center for
Theoretical Biology: Robustness, Modularity and Evolutionary Design of Living Systems
more ...
Theoretical Biology: Robustness, Modularity and Evolutionary Design of Living Systems
Affiliated scientists: (Marvin Schulz),
Edda Klipp
SFB 740
Collaborative Research Center:
From Molecules to Modules: Organisation and Dynamics of Functional Units in Cells
more ...
From Molecules to Modules: Organisation and Dynamics of Functional Units in Cells
Affiliated scientists: Wolfgang Giese, Björn Goldenbogen, Stephan Adler,
(Martha Braun),
(Aouefa Amoussouvi), (Martina Fröhlich), Edda Klipp
SysteMTb
A Collaborative Project for the Establishment of a Systems Biology Framework to Understand Key Features
of Mycobacterium Tuberculosis
more ...
Translucent-2
Modelling Ion Homeostasis in the Yeast Saccharomyces cerevisiae
more ...
Affiliated scientists: Samuel Drulhe, Falko Krause,
Mamadou Bah, (Simon Borger),
(Martina Fröhlich), (Susanne Gerber),
Edda Klipp
ViroSign
Systemvirologie von Influenza - Molekulare Signatur der permissiven Virusinfektion
more ...
Finished research projects
Aquaglyceroporins
Marie Curie Research Training Network:
Integrate Analysis of Aquaporin Structure and Function
Integrate Analysis of Aquaporin Structure and Function
Affiliated scientists: (Martina Fröhlich),
(Marcus Krantz), (Szymon Stoma),
(Carl Tiger), (Edda Klipp)
BaSysBio
Developing 'Systems Biology' Techniques to Study the Global Regulation of Gene Transcription in a Model Bacterium:
Bacillus subtilis
Affiliated scientists: (Samuel Drulhe),
(Wolfram Liebermeister), (Timo Lubitz),
(Stefan Stiller), (Edda Klipp)
CellComput
more ...
Affiliated scientists: (Marta Hoffman-Sommer),
(Marcus Krantz), (Jörg Schaber),
(Adriana Supady), (Edda Klipp)
ColoNET
A Systems Biology Approach for Integrating Molecular Diagnostics and Targeted Therapy in Colorectal Cancer
more ...
Affiliated scientists: (Thomas Handorf),
(Edda Klipp)
EMI-CD
European Modelling Initiative Combating Complex Diseases
EST Systems Biology
Marie Curie Early Stage Training in Systems Biology:
Mathematical Modeling of Aging Processes in Yeast
Mathematical Modeling of Aging Processes in Yeast
FinSysB
Marie Curie Initial Training Network:
Pathogenomics and Systems Biology of Fungal Infections - An Integrative Approach
more ...
Pathogenomics and Systems Biology of Fungal Infections - An Integrative Approach
Affiliated scientists: (Katarzyna Tyc),
Edda Klipp
GerontoMitoSys
Mitochondrial network of pathways in aging and lifespan control - a systems biology approach
more ...
IRTG
International Research Training Group: Berlin - Boston - Kyoto
Genomics and Systems Biology of Molecular Networks
more ...
Genomics and Systems Biology of Molecular Networks
Affiliated scientists: (Thomas Spießer),
(Clemens Kühn), (Gady Goldsobel),
(Christian Waltermann), Edda Klipp
Quasi
Mathematical Modeling of Stress Response and Signal Transduction in Yeast
Translucent 1
Systems Biology of Micro Organisms: Gene Interaction Networks and Models of Cation Homeostasis in
Saccharomyces cerevisiae
UNICELLSYS
Eukaryotic Unicellular Organism Biology – Systems Biology of the Control of Cell Growth and Proliferation
more ...
