Publications
2013
K. P. Bhabak, A. Hauser, S. Redmer, S. Banhart, D. Heuer, C. Arenz* "Development of a Novel FRET Probe for the Real-Time Determination of Ceramidase Activities"
ChemBioChem 2013, 14, 1049-1052.
K. P. Bhabak, C. Arenz* "Novel Drugs Targeting Sphingolipid Metabolism" (Book Chapter)
Handb Exp Pharmacol. (Editors: E. Gulbins, I Petrache) 2013, 215, 187-196.
K. P. Bhabak, B. Kleuser, A. Huwiler, C. Arenz* "Effective Inhibition of Acid and Neutral Ceramidases by Novel B-13 and LCL-464 analogues"
Bioorg. Med. Chem. 2013, 21, 874-882.
2012
K. P. Bhabak, C. Arenz* "Novel Amide- and Sulfonamide-based Aromatic Ethanolamines: Effects of Various Substituents on the Inhibition of Acid and Neutral Ceramidases"
Bioorg. Med. Chem. 2012, 20, 6162-6170
K. P. Bhabak, D. Proksch, S. Redmer, C. Arenz* "Novel Fluorescent Ceramide Derivatives for Probing Ceramidase Substrate Specificity"
Bioorg. Med. Chem. 2012, 20, 6154-6161
2011
Bhabak, K. P.; Satheeshkumar, K.; Jayavelu, S.; Mugesh, G. "Inhibition of Peroxynitrite- and Peroxidase-mediated Protein Tyrosine Nitration by Imidazole-based Thiourea and Selenourea Derivatives"
Org. Biomol. Chem. 2011, 9 , 7343-7350
Roy, G.; Bhabak, K. P.; Mugesh, G. "Interactions of Antithyroid Drugs and Their Analogues with Halogens and their Biological Implications"
Crystal Growth & Design 2011, 11(6), 2279-2286.
Bhabak, K. P.; Vernekar, A. A.; Jakka, S. R.; Roy, G.; Mugesh, G. "Mechanistic investigations on the efficient catalytic decomposition of peroxynitrite by ebselen analogues"
Org. Biomol. Chem. 2011, 9 , 5193-5200.
Bhabak, K. P.; Bhuyan, B. J.; Mugesh, G. "Bioinorganic and medicinal chemistry: aspects of gold(I)-protein complexes"
Dalton Trans. 2011, 40 , 2099-2111.
2010
Bhabak, K. P.; Mugesh, G. "Functional Mimics of Glutathione Peroxidase: Bioinspired Synthetic Antioxidants"
Acc. Chem. Res. 2010, 43(11) , 1408-1419.
Bhabak, K. P.; Mugesh, G. "Inhibition of peroxidase-catalyzed protein tyrosine nitration by antithyroid drugs and their analogues"
Inorg. Chim. Acta 2010, 363(12) , 2812-2818.
Bhabak, K. P.; Mugesh, G. "Antithyroid Drugs and their Analogues Protect Against Peroxynitrite-Mediated Protein Tyrosine Nitration-A Mechanistic Study"
Chem. Eur. J. 2010, 16(4) , 1175-1185.
2009
Bhabak, K. P.; Mugesh, G. "Synthesis and Structure-Activity Correlation Studies of Secondary- and Tertiary-Amine-Based Glutathione Peroxidase Mimics"
Chem. Eur. J. 2009, 15(38) , 9846-9854.>