Retrograde signaling results in changes in the expression of nuclear genes
(Read more at Ludwig-Maximilians-University München)
Dr. Klaus Mayer and Prof. Dr. Dario Leister | Ludwig-Maximilians-University München
Multiple signaling pathways and multiple levels of transcriptional regulation in the nucleus contribute to the complexity of retrograde signaling. From the data generated in the research team and integrating publically available data available we aim to establish a database of plastid signaling relevant expression profiles
- identify the nuclear target genes of the different pathways of plastid-to-nucleus signaling and their secondary transcriptional effects (transcriptional networks);
- characterize the overlaps and hierarchies between the different types of retrograde signaling and
- reconstruct retrograde events and identify retrograde signaling signatures in complex expression profiles.
- conserved promoter elements will be identified and enable the isolation of transcription factors